The research team led by Jo Freudenheim, epidemiologist at the University at Buffalo will have the mission to make a comparative examination of the differences in DNA methylation in electronic cigarette users, smokers and non-smokers. The goal is to compare the pulmonary reaction in each other.
A STUDY TO LEARN MORE ABOUT THE EFFECTS OF E-CIGARETTE ON THE BODY
This study attributed to an epidemiologist from the University of Buffalo therefore seeks to provide answers on the effects of e-cigarettes on the body. It is true that answers are needed since the e-cigarette has gained momentum and the Food and Drug Administration regulates it.
Jo Freudenheim, distinguished professor at the University at Buffalo and chair of the Department of Epidemiology and Environmental Health, said.The use of electronic cigarettes is increasing rapidly, including among young people who have never smoked cigarettes»
A grant from 100 000 $ from the Prevent Cancer Foundation, the only US non-profit organization dedicated exclusively to cancer prevention and early detection has been obtained. Research on the effects of electronic cigarettes is of crucial importance given the lack of knowledge regarding the health effects of users.
« There is a lot of interest in understanding how e-cigarettes can affect the body.“Said Freudenheim. " The FDA is also particularly interested in data on the biological impact of e-cigarettes. This study will contribute to that. »
The predominant ingredients of e-liquids are nicotine, propylene glycol and / or glycerol. When used in food and cosmetics, non-nicotine components are considered safe by the FDA. However, little is known about the impact these products can have on human lungs after inhalation and following the heating process that takes place in the e-cigarette.
[contentcards url = »http://vapoteurs.net/etude-e-cigarette-nest-toxique-cellules-pulmonaires-humaines/»]
WHAT PROCEDURE FOR THIS STUDY?
For this pilot study, Freudenheim and his colleagues will examine samples from the lungs of healthy smokers, non-smokers, and e-cigarette users between the ages of 21 and 30. Participants in this study underwent a procedure called bronchoscopy, where a sample of lung cells was collected through a flushing procedure.
Researchers will study the samples to see if there are differences in DNA methylation among the three groups. They will study 450 spots on tissue DNA.
« Every cell in your body has the same DNA, but parts of that DNA are activated in different tissues. Changes in DNA methylation help differentiate these cell types Says Freudenheim.
The Freudenheim study will be built on another pilot study recently started by Peter Shields, MD, of the Ohio State College of Medicine, a co-principal investigator on the Prevent Cancer Foundation grant. The goal is ultimately to seek funding for a larger study.
Jo Freudenheim has a long-standing interest in DNA methylation, focusing primarily on breast tumors, while Peter Shields has extensive experience in tobacco and e-cigarette research. They have worked together for over 20 years to find ways to prevent cancer.
Source : Buffalo.edu
