Me zai faru idan metformin, wanda shine maganin ciwon sukari, zai iya sauƙaƙa alamun cirewar nicotine kuma ta haka zai ba da gudummawa ga barin shan taba? A kowane hali, wannan shine abin da wani bincike na baya-bayan nan ya nuna.
SHIN METFORMIN YAFI INGANCI FIYE DA RUWAN NICOTINE?
Wani bincike a cikin mice (karanta a cikin Ci gaba na Cibiyar Nazarin Kimiyya ta Amirka) ya nuna cewa metformin, sanannen magani don nau'in ciwon sukari na 2, na iya sauƙaƙa alamun cirewar nicotine.
Tsawon dogon lokaci ga nicotine yana kunna wani enzyme mai suna AMPK, wanda ke cikin yankin hippocampus kuma yana shiga cikin ƙwaƙwalwar ajiya da motsin rai. An riga an nuna cewa kunna hanyar sinadarai ta AMPK na iya ba da gudummawa ga kyakkyawan yanayi na ɗan gajeren lokaci, da haɓaka ƙwaƙwalwar ajiya da maida hankali. Waɗannan halayen ba zato ba tsammani kuma gabaɗaya suna bin aikin shan taba sigari.
Barin nicotine yana dakatar da wannan ƙarfafawa, wanda zai iya ba da gudummawa ga ƙananan yanayi, rashin jin daɗi, da rashin iyawar hankali da tunawa. Tsayawa shan taba yana nufin dakatar da kunna wannan enzyme AMPK (AMP-activated protein kinase), wato yana haifar da alamun cirewa, wanda ke cikin yawancin masu shan taba. Tun da an riga an rubuta metformin don kunna AMPK, masu bincike daga Jami'ar Pennsylvania da Jami'ar Johns Hopkins sun yi mamakin ko metformin zai iya rama cirewar nicotine kwatsam.
Binciken ya gano cewa berayen da aka fallasa nicotine da aka yi wa allurar metformin kafin yaye suna nuna rage damuwa, kamar yadda aka auna ta hanyar cin abinci da gwajin aiki.
Idan ba mu ba beraye ba ne, waɗannan sakamakon farko sun fito ne daga tsarin ilimin halitta wanda ya haɗa tare, na sake kunna wannan hanyar sinadarai ta AMPK. Har zuwa yau, da 
Metformin yana da izini kawai don maganin ciwon sukari, don haka babu batun amfani da shi don rage alamun daina shan taba. Duk da haka, waɗannan sakamakon farko sun cancanci ƙarin bincike, don tabbatarwa ba kawai na ingancinsa a cikin daina shan taba ba amma har ma da inganci ga abubuwan maye gurbin nicotine. Marubutan sun rubuta:
Dangane da sakamakonmu da ke nuna ingancin metformin don rage halayen damuwa bayan cirewar nicotine, muna ba da shawarar cewa kunna AMPK a cikin kwakwalwa ta hanyar metformin ana iya ɗaukarsa azaman sabon magani don dakatar da shan taba. Metformin ya cancanci a bincika a matsayin zaɓi na warkewa don dakatar da shan taba, a cikin gwaje-gwajen asibiti na gaba, musamman tunda miyagun ƙwayoyi yana da lafiya tare da ƙarin fa'idar daidaita sarrafa sukarin jini.
source : Santelog.com/
