Kafukufuku watsopano akuwonetsa kuti Champix (Pfizer), mankhwala otchukawa kuti asiye kusuta sangathe kutsutsana ndi zomwe zanenedwa kale. kuonjezera chiopsezo cha kuvutika maganizo ndi matenda a mtima.
Phunziroli, lofalitsidwa mu Lancet (ndiponso) adatsata kuposa Odwala a 160 000 amene analandira chithandizo choloŵa m’malo mwa chikonga kwa zaka zisanu ndi mankhwala oletsa kusuta GlaxoSmithKline Zyban (bupropion) kapena kachiwiri Champix kuchokera ku Pfizer (varenicline).
Ofufuza apeza kuti anthu kutenga champix kapena Zyban sangadwale matenda a mtima kapena kudwala matenda ovutika maganizo kusiyana ndi omwe amagwiritsa ntchito njira zina. Kuonjezera apo, kugwiritsa ntchito Champix kwagwirizanitsidwa ndi chiopsezo chochepa cha matenda a mtima wa ischemic, cerebral infarction, kulephera kwa mtima, arrhythmia ndi kuvutika maganizo.
Aziz Sheikh, m'modzi mwa ochita kafukufuku komanso wotsogolera pa yunivesite ya Edinburgh's Center for Medical Informatics, anati: Kutengera kusanthula kwathu mozama, tikukhulupirira kuti ndizokayikitsa kwambiri
varenicline imakhala ndi zotsatira zoyipa kwambiri pamtima kapena m'maganizo". « Oyang'anira monga Food and Drug Administration (FDA) akuyenera kuwunikiranso chenjezo lawo lachitetezo chokhudza Champix kuti asachepetse mopanda malire mwayi wopeza chithandizo chothandiza chosiya kusuta.. "
Zotsatira zimabwera ngati nkhani yabwino Pfizer, yomwe yachita kale kafukufuku wofanana kwambiri kuti awone chitetezo cha neuropsychiatric cha mankhwala awo, zotsatira zake zidzapezeka kumapeto kwa chaka chino. Champix, yomwe idagulitsidwa ngati Chantix ku United States, idagulitsidwa padziko lonse lapansi $647 miliyoni mu 2014, zomwe zidapangitsa kuti ikhale imodzi mwazinthu zogulitsidwa kwambiri zosiya kusuta. Komabe, kupatsidwa mkangano wozungulira zotsatira zake, malonda adatsika kuyambira 2007.
Zolemba za omwe adalemba kafukufukuyu : Mphunzitsi. Daniel Kotz adalandira thandizo lopanda malire kuchokera kwa Pfizer chifukwa choyesa kusiya kusuta kunja kwa ntchito yomwe yaperekedwa ndipo imathandizidwa ndi thandizo lochokera ku Unduna wa Zatsopano, Sayansi ndi Kafukufuku wa Germany Federal State of Rhineland ku North-Westphalia.
Mphunzitsi. Robert West walandira thandizo, malipiro aumwini, ndi chithandizo chopanda ndalama kuchokera kwa Pfizer, GlaxoSmithKline, ndi Johnson & Johnson, ndi malipiro aumwini kuchokera kwa Novartis, kunja kwa ntchito yomwe yaperekedwa. Mphunzitsi. Onno CP van Schaycka adalandira thandizo lofufuzira kuchokera kwa Pfizer kunja kwa ntchito yowonetsedwa. Opanga varenicline ndi bupropion sakhudzidwa panthawi iliyonse ya polojekitiyi. Mphunzitsi. Aziz Sheikh panthawiyi amathandizidwa ndi Farr Institute, yomwe imathandizidwa ndi mgwirizano wa opereka ndalama omwe amatsogoleredwa ndi Medical Research Council ndi Commonwealth Fund; Malingaliro omwe aperekedwa pano ndi a SA osati a Commonwealth Fund, owongolera ake, maofesala, kapena antchito. Palibe kusagwirizana kwa chidwi kwa olemba maphunziro ena.
Kuyambira 2008, mankhwalawa akhala pakatikati pa milandu pafupifupi 3000, komabe, milandu yonse idathetsedwa ndi Pfizer mu June 2013.
gwero : pmlive.com
