Maawa matanhatu ekusangana nehutsi hwefodya zvakakonzera kufa kwepedyo-kwakazara kwemaseru ekuedzwa, nepo kuratidzwa kwakafanana kune e-cigarette vapor hakuna kukanganisa kushanda kwetishu.
Yakaedzwa kubva kumarudzi maviri akasiyana e-e-cigarettes, iyo mhute yakagadzirwa yakanga isina cytotoxic kukanganisa pamhepo yevanhu, maererano nekuongorora kutsva kwakabudiswa muIn Vitro Toxicology (DOI: 10.1016 / j.tiv .2015.05.018).
Masayendisiti e British American Tobacco et Iyo kambani MatTek Corporation akashandisa musanganiswa wakasarudzika webvunzo kudzidza zvingangove zvakashata zvinokonzerwa ne-e-cigarette mhute pakufema turakiti tishu uye akaienzanisa nehutsi hwefodya. "Nekushandisa muchina wefodya uye bvunzo yakavakirwa murabhoritari uchishandisa matishu ekufemesa, zvakakwanisika kuyera kusvotwa kweaerosol uye kuratidza kuti maaerosol akasiyana-siyana aripo mu e-fodya akashandiswa muchidzidzo ichi haana mhedzisiro. turakiti tishu muvanhu "anodaro mutauriri Dr. Marina Murphy.
Iyi nzira nyowani inogona kushandiswa kubatsira kukudziridza mazinga matsva emhando idzi dzezvigadzirwa mune ramangwana.
Mhepo inogadzirwa ne-e-fodya inogona kunge iine nicotine, humectants, zvinonhuhwirira uye zvinosvibisa zvinopisa zvigadzirwa, saka zvakakosha kuti unzwisise zvinogona kuitika pabiological system. Kure kure, hapasati pave nezvidzidzo zvinoratidza zvinogona kuipa mhedzisiro ye-e-cigarette vapor pane anoshandiswa mu vitro modhi anoteedzera chimiro, basa uye kuratidzwa kweakajairwa munhu ekufema tishu.
Vatsvakurudzi vakabatanidza inotengeswa 3D modhi yekufema epithelial tissue uye "Vitrocell" robhoti rinowanzo shandiswa parudzi urwu rwekuedza ne "smoke" kuongorora mukana wekushatiswa kwe e-cigarette vapor. yemhando mbiri dzinotengeswa. Mhedzisiro yacho inoratidza kuti, kunyangwe kuenderera kwemaawa ekuratidzwa, kukanganiswa kwe-e-cigarette vapor pamatishu emudumbu rekufema kwakafanana nekwemhepo. Zvakare, chidzidzo ichi chinomiririra danho rekutanga rekugarisana uye rinotangisa gakava pamusoro pezvingangove zvinotungamira zveindasitiri.
The tissue model of the breathing turakiti " EpiAirway inoratidzira masero emunhu tracheal/bronchial epithelial akagadzirwa kuti aumbe akapatsanurwa maseru akafanana nekufema turakiti epithelial tissue. The system" Vitrocell inotevedzera kufemerwa kwevanhu nekupa data inobuda kubva kumidzanga kana e-fodya. Inogona zvakare kungotumira iyo inhalation kumashure kune tishu. EpiAirway".
Vatsvagiri vakatanga kuyedza iyo biological system ine zvinozivikanwa zvinotsamwisa zvakaiswa mune yemvura fomu. Vakabva vafumura machira EpiAirway kuutsi hwefodya uye aerosols anogadzirwa kubva kumarudzi maviri e-
fodya kwemaawa matanhatu. Munguva iyi, kushanda kwesero kwakayerwa neawa imwe neimwe uchishandisa yakasimbiswa colorimetric assay. Huwandu hwehuwandu hwehuwandu hwakaiswa pachisero chepamusoro hwakaverengerwawo (uchishandisa dosimetry maturusi) kuratidza kuti utsi kana mhute yakasvika munyama mukati mekuratidzwa.
Zvigumisiro zvinoratidza kuti utsi hwefodya hunoderedza kushanda kwesero kusvika 12% (padhuze nerufu rwakakwana rwesero) mushure memaawa matanhatu. Kusiyana neizvi, hapana ye-e-cigarette aerosols yakaratidza chero kuderera kukuru kwekuita kwesero. Pasinei nemaawa e6 ekuenderera mberi kwekutsvaga, zvigumisiro zvaive zvakafanana nekudzora masero akazarurirwa kumhepo chete . Uye kunyangwe nekufumurwa zvine hasha, e-fodya yefodya haideredze kushanda kwesero.
«Parizvino, hapana zviyero zvine chekuita nekuyedza in vitro ye e-fodya aerosols ", anodaro Marina Trani, mukuru weR&D wezvigadzirwa zvechikakananda zveBritish American Fodya. Asi, anowedzera,Protocol yedu inogona kubatsira zvakanyanya mukubatsira maitiro kuti aenderere mberi.»
Ichi chidzidzo chinoratidza kuti, mumuenzaniso uyu wekufema kwevanhu, cytotoxicity haina kukanganiswa ne-e-cigarette aerosols, asi zvimwe zvidzidzo zvichadiwa kuenzanisa migumisiro yezvimwe zvakasiyana-siyana zvinotengeswa zvinotengeswa, mafomati uye maitiro.
mabviro : Eurekalert.org
