Saamaynta caafimaad ee muddada dheer ee sigaarka elektaroonigga ah ayaa weli ah mid aan la garanayn, laakiin kuwan Jaamacadda North Carolina toxicologists waxay tusinaysaa in isticmaalkoodu aanu fududayn hiddo-wadaha ku lug leh difaaca difaaca ee mareenka neef-mareenka sare. Marka aan sigaar cabno, daraasiin hidde-sideyaal ah oo ku lug leh difaaca difaaca ayaa beddela unugyada epithelial ee ku xiran marinnada hawada. Isticmaalka sigaarka elektaroonigga ah wuxuu yeelan doonaa saameyn isku mid ah adduunka oo dhan. Gabagabada lagu daabici doono Joornaalka Maraykanka ee Physiology kuwaas oo ku xidhiidhiya isbeddeladan epigenetic-ka iyo khatarta sii kordheysa ee caabuqyada iyo bararka.
Bayaan ka soo baxay Jaamacadda, hogaamiyaha qoraaga, Dr. Ilona Jaspers, oo ah borofisar ku takhasusay cudurrada carruurta iyo microbiology iyo immunology ayaa sheegtay inay la yaabtay natiijooyinkan. Cilmi-baaristu waxay si gaar ah u soo jeedinaysaa in neefsashada dareeraha uumiga leh ee sigaarka elektaroonigga ah aysan saameyn la'aan ku yeelan heerka muujinta hidda-wadaha unugyada epithelial. Neefsashadani waxay u horseedi doontaa isbeddellada epigenetic, taas oo ah in la yiraahdo muujinta hidda-socodka iyo sidaas darteed soo saarista borotiinnada muhiimka u ah caafimaadka unugyadeena.
Muuqaal ahaan iyo shaqo ahaanba, lakabyada epithelial ee marinnada sankeena waxay aad ugu eg yihiin lakabyada epithelial ee sambabadayada. Dhammaan unugyada epithelial ee ku teedsan marinnada hawadeenna ee sankayaga ilaa bronkiolesyada yaryar ee sambabadayadu waxay u baahan yihiin inay si habboon u shaqeeyaan si ay u qabtaan oo ay uga saaraan walxaha iyo cudur-sidaha si ay u yareeyaan khatarta caabuqa iyo caabuqa. Unugyadan epithelial ayaa sidaas darteed lagama maarmaan u ah difaaca caadiga ah ee difaaca. Hido-sideyaasha qaarkood ee unugyadan waa in ay u codeeyaan xaddi ku filan oo borotiinno ah, kuwaas oo habeeya jawaabta guud ee difaaca. Waxaa muddo dheer la ogaa in sigaar-cabbiddu ay beddesho muujinta hidde-sidayaashan, taas oo ka caawisa sharraxaadda sababta sigaar-cabbiddu ay aad ugu nugul yihiin cilladaha sare ee neef-mareenka.
Isku day lagu qiimeynayo saameynta sigaarka elektaroonigga ah ee hiddo-wadaha ku lug leh ilaalinta mareenkeenna neef-mareenka sare, kooxdu waxay falanqeysay muunadaha dhiigga iyo kaadida ee 13 aan sigaarka cabbin, 14 sigaar cabba iyo 12 e-isticmaalka. -sigaarka, si loo qeexo heerarka nikotiinka. Ka qaybgale kasta waxa kale oo uu haystay xusuus-qor uu ku diiwaangelinayo cabbista sigaarka ama isticmaalka sigaarka elektaroonigga ah. 3 toddobaad ka dib, cilmi-baarayaashu waxay ka qaadeen muunado ka qaybgalayaasha marinnada sanka si ay u falanqeeyaan muujinta hidda-socodka muhiimka u ah jawaabta difaaca. Kooxdu waxay ogaatay in,
- sigaarku wuxuu yareeyaa muujinta 53 hidde-sidayaasha muhiimka u ah jawaabta difaaca unugyada epithelial;
- Sigaarka elektaroonigga ah wuxuu yareeyaa muujinta 358 hidde-sideyaasha muhiimka u ah difaaca difaaca, oo ay ku jiraan 53 hidde-sideyaasha ku lug leh kooxda sigaarka cabba.
Cilmi-baadhayaashu waxay qoreen in ay mid mid u barbar dhigeen hidde-sidayaashan waxayna ogaadeen in hidde-side kasta oo ka mid ah labada kooxood uu ka badan yahay " aamusan mar labaad kooxda sigaarka elektaroonigga ah. Si kastaba ha ahaatee, markan waxay 
ku soo gunaanado darnaanta saamaynta labada dhaqan.
Marxaladdan, kuwani waa indho-indheyn molecular kuwaas oo aan weli lala xidhiidhin saamaynta caafimaad ee muddada dheer ee isticmaalka sigaarka elektaroonigga ah ama khatarta sii kordheysa ee cudurrada qaarkood - sida horeba loogu muujiyay tubaakada (kansarka, emphysema, cudurrada sambabada ee joogtada ah ...). Cilmi-baadhayaashu waxay qireen in aanay weli aqoonsan saamayntan muddada-dheer, laakiin waxay qiyaasayaan inay noqon doonaan " oo ka duwan saamaynta sigaarka " Su'aashu waxay weli tahay saamaynta muddada-dheer, cudurrada sida COPD, kansarka ama emphysema oo qaadanaysa sannado si ay ugu koraan sigaarka. Cilmi baaris dheeraad ah ayaa lagu qorsheeyay unugyada epithelial ee isticmaalayaasha sigaarka elektaroonigga ah…
Ilaha : - Joornaalka Maraykanka ee Fiisioloji (In Press) iyo Daryeelka Caafimaadka ee UNC Juun 20, 2016 (Isticmaalka sigaarka elektaroonigga ah wuxuu beddeli karaa boqollaal hidde-sideyaal ah oo ku lug leh difaaca difaaca marinnada hawada)
– Santelog.com
