Iziphumo zezempilo zexesha elide ze-e-cigarettes zihlala zingaziwa kakhulu, kodwa ezi KwiYunivesithi yaseNorth Carolina toxicologists ibonisa ukuba ukusetyenziswa kwabo akuyonto encinci kwiijini ezibandakanyekayo ekukhuseleni umzimba wendlela yokuphefumula ephezulu. Xa sitshaya icuba, uninzi lwemizila yemfuza ebandakanyekayo kukhuselo lomzimba luyaguqulwa kwiiseli ze-epithelial ezihamba kwindlela yomoya. Ukusetyenziswa komdiza we-elektroniki kuya kuba neziphumo ezifanayo kwihlabathi jikelele. Izigqibo ziya kupapashwa kwi Ijenali yaseMelika yePhysiology abanxulumanisa olu tshintsho lwe-epigenetic kunye nomngcipheko owonyukayo wosulelo kunye nokudumba.
Kwingxelo evela kwiYunivesithi, umbhali okhokelayo, uDkt Ilona Jaspers, uprofesa wezifo zabantwana kunye ne-microbiology kunye ne-immunology uthe wamangaliswa zezi ziphumo. Uphando lucebisa ngokuthe ngqo ukuba ukuphefumla kolwelo olwenziwe umphunga nge-e-cigarettes akukho ziphumo kumgangatho wokubonakaliswa kofuzo lweeseli ze-epithelial. Oku kuphefumla kuya kubangela ukuguqulwa kwe-epigenetic, oko kukuthi kwi-gene expression kwaye ngoko ke ukuveliswa kweeprotheni ezibalulekileyo kwimpilo yeeseli zethu.
Ngokubonakalayo kunye nokusebenza, iileyi ze-epithelial zemiphunga yethu yeempumlo zifana kakhulu ne-epithelial layers yemiphunga yethu. Zonke iiseli ze-epithelial ecaleni kwendlela yethu yomoya ukusuka empumlweni yethu ukuya kwi-bronchioles encinci kwimiphunga yethu kufuneka isebenze ngokufanelekileyo ukuze ibambe kwaye isuse amasuntswana kunye ne-pathogens kwaye ngaloo ndlela inciphisa umngcipheko wokusuleleka kunye nokuvuvukala. Ezi seli ze-epithelial ke ngoko ziyimfuneko kukhuselo oluqhelekileyo lokhuselo lomzimba. Ezinye iijini kwezi seli kufuneka zikhuphe izixa ezaneleyo zeeprotheyini, eziququzelela impendulo yonke yomzimba. Kudala kusaziwa ukuba ukutshaya kuyayitshintsha indlela athetha ngayo la mizila yemfuza, nto leyo enceda ekucaciseni isizathu sokuba abantu abatshayayo babe sesichengeni sokuphazamiseka kwendlela yokuphefumla.
Ngomzamo wokuvavanya imiphumo ye-e-cigarettes kwiigene ezibandakanyekayo ekukhuseleni indlela yethu yokuphefumula ephezulu, iqela lihlalutye iisampulu zegazi kunye nomchamo ukusuka kwi-13 abangabhemi, ababhemayo be-14 kunye nabasebenzisi be-e-cigarette be-12. amanqanaba enikotini. Umthathi-nxaxheba ngamnye ukwagcine idayari echaza ukutshaya kwabo icuba okanye ukusebenzisa i-e-cigarette. Emva kweeveki ze-3, abaphandi bathatha iisampulu kwiimpumlo zabathathi-nxaxheba ukuhlalutya ukubonakaliswa kwemfuza ebalulekileyo ekuphenduleni komzimba. Iqela lifumanisa ukuba,
- imidiza inciphisa ukubonakaliswa kwemfuza ye-53 ebalulekileyo ekuphenduleni komzimba kwiiseli ze-epithelial,
- i-e-cigarette inciphisa ukubonakaliswa kwe-358 yofuzo ebalulekileyo ekukhuseleni umzimba, kubandakanywa ne-53 izakhi zofuzo ezibandakanyekayo kwiqela lababhemayo.
Abaphandi babhala ukuba bathelekisa le mizila yemfuza nganye nganye kwaye bafumanisa ukuba uhlobo ngalunye oluqhelekileyo kuwo omabini amaqela lungaphezulu “ lemvula kwakhona kwiqela le-e-cigarette. Nangona kunjalo, ngeli xesha, baya 
sigqibe ngobungqongqo beziphumo zezi zenzo zimbini.
Kweli nqanaba, olu luqwalaselo lwemolekyuli ezingekadibanisi nemiphumo yempilo yexesha elide ukusuka ekusebenziseni i-e-cigarettes okanye ukwanda komngcipheko wezifo ezithile - njengoko sele kubonisiwe ngecuba (umhlaza, i-emphysema, isifo esingapheliyo se-pulmonary obstructive ...). Abaphandi bayavuma ukuba abakachongi ezi ziphumo zexesha elide kodwa baqikelele ukuba baya kuba " yahlukile kwimiphumo yecuba ". Umbuzo uhlala ungowokuchaphazeleka kwexesha elide, izifo ezinje ngeCOPD, umhlaza okanye i-emphysema ezithatha iminyaka ukukhula kubantu abatshayayo. Uphando olongezelelweyo lucetywa kwiiseli ze-epithelial zabasebenzisi be-e-cigarette…
imithombo : - Ijenali yaseMelika yePhysiology (Kushicilelo) kunye ne-UNC yezeMpilo ngoJuni 20, 2016 (Ukusetyenziswa kwe-E-cigarette kunokuguqula amakhulukhulu emfuza abandakanyekayo ekukhuseleni umzimba womoya)
–Santelog.com
