Olu phononongo oluvela kwiYunivesithi yaseBristol lusizisela idatha entsha kraca malunga neziphumo zentliziyo ye-e-cigarettes, xa kuthelekiswa necuba eliqhelekileyo. I-e-cigarette ye-elektroniki isaphawula inqaku: iiseli zethu zentliziyo, abantu, azigxininiswe ngumphunga we-e-cigarette njengoko zinjalo ngumsi wecuba lendabuko. Ubungqina obutsha, kwisiphumo esingekaphononongwa ukuza kuthi ga ngoku ukuba sifundwe kwijenali yeDrug and Alcohol Dependence.
Ukukhula kokusetyenziswa kwe-e-cigarettes, ehambisa i-nicotine nge-inhalation, ngokukhawuleza kunophando kunye nokudibanisa idatha yesayensi kulo mbandela. Ukuqhuba uphando ngeziphumo zebhayoloji kubalulekile, ngakumbi kwiziphumo zentliziyo eziphantse zingabhalwanga. Abaphandi baseBristol ke ngoko bakhethe ukufunda impendulo yeeseli zentliziyo kuxinzelelo olunxulumene nomphunga we-e-cig. Okanye umsi we-e-cigarette. Ngokukodwa, abaphandi bajonge indlela iiseli ezikhoyo kwimithambo yentliziyo, ebizwa ngokuba ziiseli ze-coronary artery endothelial, zisabela ekuvezweni kwi-e-cigarette vapor vs.
Inkcubeko yeseli yavezwa kwiincindi zomphunga we-e-cigarette kunye nomsi wecuba oqhelekileyo. Abaphandi bahlalutya iiprofayili zokubonisa imfuza yeeseli zentliziyo ukuvavanya impendulo yabo kuxinzelelo. Bachonga utshintsho kwi-gene expression yezi seli zentliziyo emva kokuvezwa komsi wecuba kodwa hayi emva kokuvezwa ngumphunga we-e-cigarette.
Esi siphumo sibonisa inzuzo entsha ekutshintsheni kwi-cigarettes yendabuko ukuya kwi-e-cigarettes, ababhali baphetha.
imvelaphi : Ukuxhomekeka kweziyobisi kunye noTywala May, 2016 DOI: 10.1016/j.drugalcdep.2016.04.020 Umsi wecuba kodwa hayi i-aerosol yecuba ye-elektroniki yenza impendulo yoxinzelelo kwi-coronary artery endothelial cell kwinkcubeko. (inguqulelo ngu santelog.com)
