Uphononongo olutsha olulungele imidiza ye-elektroniki oluqhutywe kwi-Pasteur Institute yeSibhedlele seYunivesithi yaseLille lwapapashwa kule nyanga. Ibalaseliswe ngugxa wethu osuka ipolitiki, lo msebenzi kwakhona ubonisa " ityhefu esezantsi yomphunga xa kuthelekiswa nomsi wecuba".
I-VAPE IXESHA NGAPHANTSI KUNESIGARETTE KWIBRONCHI
Ukufikelela kwesi sigqibo, Sebastien Antherieu kunye neqela lakhe lophando baveze iiseli kumsi wecuba kunye nomphunga we-e-cigarette ngokuvelisa iimeko ezingokoqobo zokusetyenziswa. Uxwebhu olukhoyo kwi ijenali yeToxicology in vitro cacisa ukuba "Ngelixa umsi wecuba unciphise kakhulu ukusebenza kweeseli emva kwemizuzu engama-48 yokuvezwa, ukufunxa akuzange kubangele nayiphi na i-cytotoxicity emva kwemizuzu engama-288 yokuvezwa.».
Ukongeza, iqela le Impembelelo yeekhemikhali zokusingqongileyo kwimpilo yabantu (IMPECS) yenze novavanyo lweziphumo kwimizila yemfuza. “Idatha ye-transcriptomic esuka kwiiseli eziveziweyo ibonisa inani elikhulu lemizila yemfuza engalawulwayo ekuphenduleni umsi wecuba (…)».
Ukuqukunjelwa kolu phononongo lwetyhefu olwenziwe kwiZiko lePasteur leSibhedlele seYunivesithi yaseLille kwiiseli ze-bronchial epithelial kucacile: “Ezi ziphumo zibonisa ngamandla ubutyhefu obuphantsi bomphunga xa kuthelekiswa nomsi wecuba».
UMQATHANGO WOKUKWENZA UMSEBENZI
Injongo yolu phononongo yayikukuvavanya i-vaping phantsi kweemeko zokwenyani ukuze kubonwe ukuba ingaba ibangela ubutyhefu na emva kokuvezwa ngokuqatha nangokuphindaphindiweyo, kunye nokuthelekisa iziphumo zayo nezo zomsi wecuba.
Iqaliswe ngo-Matshi 2014, uphando lusebenzise i-cigarettes yophando oluqhelekileyo (3R4F) kunye nezixhobo ezine-clearomizer kunye ne-ego-type ibhetri kwi-3,7 volts, enikezelwa yi-brand ye-Lille i-Nhoss, efakwe i-2,8 Ohm resistors. Ulwelo lwesiFrentshi lweentlobo ezintathu - ngaphandle kwevumba, kunye necuba eli-blond kunye ne-chlorophyll mint flavour nganye kwi-version ye-nicotine-free kunye nesantya se-16mg / ml. Ukuvezwa kweeseli ze-BEAS-2B kwi-steam kwenziwa nge-air-liquid interface (ALI) ukuvelisa kwakhona iimeko ezingokoqobo zokusetyenziswa. “Le nkqubo iyakwazi ukuvisisanisa iimeko zobomi bokwenene yaye ixelisa ngokunyanisekileyo imeko yokuncipha, ukuqukuqela nokufuma komphunga okanye ukutshaya,” ibalaselisa uhlolisiso, ithatha amanqaku asuka kwiimbekiselo zalo mbandela.
«Ngokungabikho kweprofayili ye-vaping esemgangathweni, umthamo ophezulu we-puff kunye ne-frequency yakhethwa. Ukugqabhuka kwachazwa ngomthamo we-55 ml ehlala imizuzwana emi-3, ithathwe kwi-30 sec intervals, usebenzisa iprofayili yokuqhuma kwamaza.". Ngokwahlukileyo, i-cigarette puffs imele umthamo we-35 ml kwimizuzwana ye-2, ithathwe yonke imizuzwana ye-60, ilandela umgangatho owaziwayo we-ISO kwisifundo (ISO 3308: 2012). Indawo " ipolitiki »ngoko ichaza " ukuba ngokufutshane, ukufunxa kuphantsi kolawulo lokufunxa okunamandla ngakumbi kwaye ngokuphindwe kabini kunomsi wecuba. »
Ekugqibeleni, olu phononongo luphinda luqaqambise into yokuba ukusetyenziswa kwecuba ze-elektroniki kunokuthathwa njengenye indlela yokutshaya.
imvelaphi : Vapolitics.blogspot.fr/
Isalathiso sokufunda :
Ukuthelekiswa kweeseli kunye neempembelelo ze-transcriptomic phakathi komphunga we-elektroniki wecuba kunye nomsi wecuba kwiiseli ze-bronchial epithelial.
uSébastien Anthérieu, u-Anne Garat, uNicolas Beauval, uMélissa Sé, uDelphine Allorge, uGuillaume Garçon noJean-Marc Lo-Guidice; ukusuka kwiYunivesithi. Lille, CHU Lille, Institut Pasteur de Lille, EA 4483 – IMPECS – Impembelelo yeMichiza yokuSingqongileyo kwimpilo yabantu
kwiToxicology eVitro, TIV 3902, doi: 10.1016/j.tiv.2016.12.015
