Imiphumela yesikhathi eside yezempilo kagwayi we-elekthronikhi ayikaziwa kakhulu, kodwa lokhu I-University of North Carolina toxicologists kubonisa ukuthi ukusetshenziswa kwabo akuyona into encane ezakhini zofuzo ezihilelekile ekuvikelweni kwamasosha omzimba wendlela yokuphefumula ephezulu. Lapho sibhema ugwayi, inqwaba yezakhi zofuzo ezihilelekile ekuzivikeleni komzimba ziyashintshwa kumangqamuzana e-epithelial asemgwaqweni womoya. Ukusetshenziswa kukagwayi we-elekthronikhi kuzoba nemiphumela efanayo emhlabeni jikelele. Iziphetho zizoshicilelwa ngo I-American Journal of Physiology abahlobanisa lezi zinguquko ze-epigenetic nengozi eyandayo yokutheleleka nokuvuvukala.
Esitatimendeni esivela eNyuvesi, umbhali oholayo, uDkt. Ilona Jaspers, uprofesa wezifo zezingane kanye ne-microbiology kanye ne-immunology uthe wamangala ngale miphumela. Ucwaningo luphakamisa ngokuqondile ukuthi ukuhogela koketshezi oluhwamukile ngogwayi we-elekthronikhi akunayo imiphumela ezingeni lokuvezwa kofuzo lwamaseli e-epithelial. Lokhu kuphefumula kungaholela ekuguqulweni kwe-epigenetic, okusho ukuthi ekukhulumeni kwezakhi zofuzo ngakho-ke ekukhiqizeni amaprotheni abalulekile empilweni yamangqamuzana ethu.
Ngokubukeka kanye nokusebenza, izingqimba ze-epithelial zezingxenye zethu zamakhala zifana kakhulu nezingqimba ze-epithelial zamaphaphu ethu. Wonke amangqamuzana e-epithelial eduze kwendlela yethu yokuphefumula esuka ekhaleni yethu kuya kuma-bronchioles amancane emaphashini ethu adinga ukusebenza kahle ukuze abambe futhi asuse izinhlayiya kanye namagciwane futhi ngaleyo ndlela anciphise ingozi yokutheleleka nokuvuvukala. Ngakho-ke lawa mangqamuzana e-epithelial abalulekile ukuze kube nokuzivikela okujwayelekile komzimba. Izakhi zofuzo ezithile kulawa maseli kufanele zibhale amanani anele amaprotheni, ahlela ukusabela komzimba wonke. Sekuyisikhathi eside kwaziwa ukuthi ukubhema kushintsha ukubonakaliswa kwalezi zakhi zofuzo, okusiza ekuchazeni ukuthi kungani ababhemayo besengozini enkulu yokuphazamiseka kwemigudu yokuphefumula ephezulu.
Emzamweni wokuhlola imiphumela kagwayi we-elekthronikhi ezakhini zofuzo ezihilelekile ekuvikeleni umgudu wethu wokuphefumula ophezulu, ithimba lahlaziya amasampula egazi nomchamo kubantu abangu-13 abangabhemi, abangu-14 ababhemayo kanye nabasebenzisa i-e-ugwayi abangu-12. -ugwayi, ukuze kucaciswe amazinga e-nicotine. Umhlanganyeli ngamunye uphinde wagcina idayari ebhala ngokubhema kwakhe ugwayi noma ukusetshenziswa kukagwayi we-e. Ngemva kwamaviki angu-3, abacwaningi bathatha amasampula ezingxenyeni zekhala zabahlanganyeli ukuze bahlaziye ukubonakaliswa kwezakhi zofuzo ezibalulekile ekuphenduleni kwamasosha omzimba. Iqembu lithola ukuthi,
- ugwayi wehlisa ukubonakaliswa kwezakhi zofuzo ezingama-53 ezibalulekile ekuphenduleni kokuzivikela komzimba kwamaseli e-epithelial,
- i-e-cigarette inciphisa ukubonakaliswa kwezakhi zofuzo ze-358 ezibalulekile zokuzivikela komzimba, kuhlanganise nezakhi zofuzo ze-53 ezihilelekile eqenjini lababhemayo.
Abacwaningi babhala ukuthi baqhathanisa lezi zakhi zofuzo ngamunye ngamunye futhi bathola ukuthi isakhi sofuzo esivamile kuwo womabili amaqembu singaphezulu “ ingezwakali futhi eqenjini le-e-cigarette. Nokho, kuleli qophelo 
siphethe ngobunzima bemiphumela yale mikhuba emibili.
Kuleli qophelo, lokhu kuwukubhekwa kwamangqamuzana okungakahlotshaniswa nemiphumela yezempilo yesikhathi eside kusukela ekusetshenzisweni kukagwayi we-elekthronikhi noma ingozi eyengeziwe yezifo ezithile - njengoba sekubonisiwe kakade ngogwayi (umdlavuza, i-emphysema, isifo se-chronic obstructive pulmonary…). Abacwaningi bayavuma ukuthi abakayiboni le miphumela yesikhathi eside kodwa bacabanga ukuthi izoba " ehlukile emiphumeleni kagwayi ". Umbuzo usamile ukuthi emiphumeleni yesikhathi eside, izifo ezifana neCOPD, umdlavuza noma i-emphysema ezithatha iminyaka ukukhula kwababhemayo. Ucwaningo olwengeziwe luhlelelwe amaseli e-epithelial abasebenzisi baka-e-cigarette…
Imithombo : - I-American Journal of Physiology (In Press) kanye ne-UNC Health Care June 20, 2016 (Ukusetshenziswa kukagwayi we-elekthronikhi kungashintsha amakhulukhulu ezakhi zofuzo ezibandakanyeka ekuvikelweni kokuzivikela komzimba emoyeni)
– Santelog.com
