Ucwaningo olusha lubonisa ukuthi i-Champix (Pfizer), lo muthi odumile wokuyeka ukubhema awukwazi ukungqubuzana nalokho okushiwo esikhathini esidlule. kwandisa ingozi yokucindezeleka nokuhlaselwa yinhliziyo.
Ucwaningo, olushicilelwe ku I-Lancet (futhi nabo) balandele okungaphezu kwalokho Iziguli ze-160 000 owathola ukwelashwa esikhundleni se-nicotine iminyaka emihlanu ngomuthi wokunqanda ukubhema I-GlaxoSmithKline Zyban (bupropion) noma I-Champix evela ku-Pfizer (varenicline).
Abacwaningi bathole ukuthi abantu abathathayo I-Champix noma Zyban mancane amathuba okuba bahlaselwe yinhliziyo noma babe nezimpawu zokucindezeleka kunalabo abasebenzisa ezinye izindlela. Ngaphezu kwalokho, ukusetshenziswa kwe-Champix kuye kwahlotshaniswa nengozi encishisiwe kakhulu yesifo senhliziyo ye-ischemic, i-cerebral infarction, ukwehluleka kwenhliziyo, i-arrhythmia nokucindezeleka.
Aziz Sheikh, omunye wabacwaningi balolu cwaningo kanye nomqondisi wesikhungo se-University of Edinburgh's Center for Medical Informatics, uthe: Ngokusekelwe ekuhlaziyeni kwethu okujulile, sikholwa ukuthi mancane amathuba okuthi lokho
i-varenicline inemiphumela emibi kakhulu enhliziyweni noma empilweni yengqondo”. " Abalawuli abafana ne-Food and Drug Administration (FDA) kufanele babuyekeze isixwayiso sabo sokuphepha mayelana ne-Champix ukuze bangakhawuleli ngokungenasidingo kulolu sizo olusebenzayo lokuyeka ukubhema.. "
Imiphumela iza njengezindaba ezinhle Pfizer, esivele yenze ucwaningo olufanayo kakhulu lokuhlola ukuphepha kwe-neuropsychiatric yemikhiqizo yabo, imiphumela ezotholakala kamuva kulo nyaka. I-Champix, imakethwa njenge-Chantix e-United States, yadayiswa emhlabeni wonke ngezigidi ezingu-647 zamaRandi ngo-2014, okuyenza ibe ngesinye sezidakamizwa ezidayiswa kakhulu zokuyeka ukubhema. Nokho, inikezwe impikiswano ezungeze imiphumela yayo, ukuthengiswa kwehle kusukela ngo-2007.
Inothi mayelana nababhali bocwaningo : Uthisha. Daniel Kotz ithole uxhaso olungakhawulelwe oluvela ku-Pfizer ngesivivinyo sokuyeka ukubhema ngaphandle komsebenzi owethuliwe futhi isekelwa uxhaso oluvela ku-Ministry of Innovation, Science and Research of the German Federal State of Rhineland of North-Westphalia.
Uthisha. Robert West uthole izibonelelo, izimali zomuntu siqu, nokusekelwa okungezona ezemali okuvela ku-Pfizer, GlaxoSmithKline, no-Johnson & Johnson, kanye nezimali zomuntu siqu ezivela kwa-Novartis, ngaphandle komsebenzi owethulwe. Uthisha. Onno CP van Schaycka uthole uxhaso locwaningo ku-Pfizer ngaphandle komsebenzi ofakiwe. Abakhiqizi be-varenicline ne-bupropion ababandakanyekanga kunoma yisiphi isigaba sale phrojekthi. Uthisha. Aziz Sheikh okwamanje isekelwa i-Farr Institute, esekelwe yinhlangano yabaxhasi bezimali eholwa yi-Medical Research Council kanye ne-Commonwealth Fund; imibono evezwe lapha ngeye-SA futhi hhayi eye-Commonwealth Fund, abaqondisi bayo, izikhulu, noma abasebenzi. Akukho ukungqubuzana kwezintshisekelo zabanye ababhali bocwaningo.
Kusukela ngo-2008, umuthi ubuphakathi kwamacala acishe abe yi-3000, nokho-ke, wonke amacala axazululwa nguPfizer ngoJuni 2013.
Umthombo : pmlive.com
