STUDY: Can e-cigarettes lead to impaired lung function?

STUDY: Can e-cigarettes lead to impaired lung function?

15 Despite the many studies on the subject, it remains difficult to pronounce definitively. Yet a new study published in the American Journal of Physiology concluded that the flavoring and additive ingredients contained in e-liquids may impair lung function.


AN E-CIGARETTE STUDY THAT USES MICE AGAIN


The flavoring ingredients and additives contained in e-liquids can alter lung function, in any case this is what a new study has just concluded by Greek researchers from the University of Athens. The study, published in the American Journal of Physiology, also found that short-term exposure to e-cigarette vapor was sufficient to cause lung inflammation similar to or worse than that seen with traditional cigarette smoking.

The researchers studied several groups of mice who were exposed four times a day to various combinations of chemicals. Each exposure session was separated by 30-minute smoke-free intervals.

One group was exposed to cigarette smoke (" cigarette"), Another with e-cigarette vapor containing propylene glycol and vegetable glycerin (" propylene"). A third was exposed to e-cigarette vapor containing propylene glycol and nicotine (" propylene + nicotine") And a fourth was exposed to e-cigarette vapor containing propylene glycol, nicotine and a tobacco flavor (" aroma").

The groups were compared to a control group exposed to good quality air. Some animals in each group were exposed to short-term cigarette smoke or e-cigarette vapor (three days), while others were exposed for a longer period (four weeks). 


AN INCREASE IN INFLAMMATION MARKERS


The research team found an increase in markers of inflammation, mucus production and impaired lung function in the " propylene"," propylene + Nicotine " and " aroma After three days. However, the “propylene” group showed less negative effects with long-term exposure, suggesting that the additive alone causes only temporary irritation which eventually goes away with continued use. 

Additionally, two proteins responsible for inflammation became elevated only in the “flavor” group, indicating that some of the many flavoring components on the market may not be safe even for short-term use.

The state of the “e-cigarette” groups compared to the “cigarette” group surprised the researchers. The stress level of cells in the "aroma" group was equal to or greater than that of the "cigarette" group.

« Harmful effects observed in lungs exposed to e-cigarette vapors underscore the need for further study of the safety and toxicity of these expanding devices worldwide“, Conclude the researchers.

Source : Physiology.org/ - Pourquoidocteur.fr/

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